Kidney Art – O'Brien Lab

Six2+ nephron progenitors, all colors!

Cap niches captured via a Zeiss 880 confocal microscope, 60x mag

Forming nephron. Orange: Pax2, Blue: Cytokeratin

Cap niches, Blue: Six2, Yellow: Cytokeratin

Glomerulus

P0 wholemount image taken at P0 using a LaVision BioTec UltraMicroscope II Light-Sheet Scope. Red: CD31, Green: Tuj1, Blue: Calbindin 2.5x magnification

Cap niches at P0. Green: Six2, Blue: Cytokeratin

Kidney organoid, captured via a Zeiss 880 confocal microscope, 20x magnification

Adult kidney vasculature

Nephron progenitor extension. Red: GFP, Cyan: Six2, Green: Cytokeratin